For many, the solutions to our most complex disease problems — cancer, Alzheimer’s, diabetes, to name a few — remain painfully elusive. Why, in the era of the Human Genome Project, modern molecular biology and genetics and incredibly detailed scans of our innermost regions, do these conditions defy our attempts to understand and cure them?
As a physician-investigator of chronic brain diseases, I have felt the frustration of watching many of my patients — all of them innocents — lose control over their bodies and minds. All the while I realized that we know so much about the cellular problems in their brains but have so few therapies to offer. And there are thousands like me who study the diseases of man with the hope that more knowledge means better treatments and less suffering to patients and families.